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Home >> Consumer Info >> Continence Info - Adults >> Medications and Continence

Medications and Continence

Diuretics

Frusemide (Lasix, Frumil)

Bendrofluazide (Aprinox)

Cyclopenthiazide (Navidrex)

Cause urine to be produced, more marked for Frusemide. Used in the treatment of heart failure, high blood pressure, leg swelling and a number of other conditions. Can contribute to urinary frequency, urgency and urge incontinence.

Drugs with anticholinergic effects.

Many different drug classes have this effect.

Tricyclic anti-depressants

Major tranqullizers/Anti-psychotics

Anti-Parkinson's disease agents

Anti-histamines

Anti-spasmodics

Pain relievers

Oxybtynin (Ditropan)

Heridone (Detrusitol)

Amitryptiline (Amitrip, Tryptanol) Doxepin, Imipramine (Sinequan)

Thioridazine (Melleril)

Orphenadrine (Disipal) Benztropine (Cogentin) Hydroxyzine (Atarax) Promethazine (Phenergan) Hyoscine (Buscopan) Dicyclomine (Merbentyl)

Nefopam (Acupan)

These drugs block the action of the chemical acetylcholine.

They cause the bladder muscle to contract less strongly and can contribute to urinary retention. Not all drugs in any drug class have this effect.

Sedative agents including benzodiazepines and other sleeping pills Temazepam (Normison) Diazepam (D Pam) These drugs can reduce awareness of bladder filling and also decrease balance thus increasing the risk of falls.
Narcotic analgesics Morphine (MST) Codeine (Panadeine) Dextropropxyphene (Paradex) These drugs can reduce awareness of bladder filling and cause constipation which can contribute to bladder control problems.
Alpha blocking agents Terazosin (Hytrin BPH) Doxazosin (Cardoxan/Dosan) Used for high blood pressure and in men with reduced urine flow related to an enlarged prostate gland.

Can contribute to stress urinary incontinence in women.

Alpha activating agents Pseudoephedrine (in numerous cold remedies such as Coldrex) Can increase symptoms of urine flow obstruction related to the prostate.
Beta agonists Salbutamol (Venblin) Used in the treatment of asthma.

Can reduce the strength of bladder muscle contraction.

Calcium channel blockers Nifedipine (Adalat) Verapamil (Isoptin) Used in treatment of high blood pressure and angina. Can reduce the strength of bladder muscle contraction and contribute to constipation.

Medications can be very helpful in treating bladder control problems. However, in some people medications can affect bladder control and the ability to get to and use the toilet. This is more likely in older people who may be on several different types of medication. Usually for people with bladder control problems, medications are only part of a bigger picture. Sorting out a continence problem may well involve a lot more than just adjusting medications.

Medication may be very important for other aspects of a person's health. The decision to alter medication by stopping and/or adjusting the number and type of drugs should be done after careful thought and discussion with who ever prescribed the medication, usually a doctor.

Medications are known by a number of different names. Firstly they may be known by the 'class' effect. For example antibiotics are medications which act against bacteria which cause infections. Secondly they may be known by their specific name, for example a particular antibiotic used for urinary tract infections is Trimethoprim. Finally the drug may have a trade name, which is the particular brand a drug company manufactures, for example brands of Trimethoprim are Triprim (made by Glaxo Wellcome) and TMP (made by Pacific).

In the table, the first column is the general classes of drug, the second column contains particular specific examples with some brands of the specific examples in brackets, and the third column describes the usual use and potential effects on bladder control. These effects, intended or otherwise, do not happen to everyone. This list is not a complete list. Brands may change and many different medications may be found to contribute to or help with bladder control problems. Looking up the medication in a drug information book such as 'New Ethicals', discussion with a pharmacist, reading the manufacturer's material, or discussion with a doctor or health professional may all be needed to decide what is best for a particular person.

Do you have any questions?

Other titles available include:

  • Good Bladder Habits
  • Bladder Control Problems in Women
  • Urinary Symptoms in Men
  • Pelvic Floor Muscle Training in Women
  • Pelvic Floor Muscle Training in Men
  • Bladder Retraining
  • Incontinence in Children-Bedwetting &
  • Daytime Problems
  • Healthy Bowel - Bowel Control Problems
  • Dementia & Urinary Incontinence
  • Older People & Continence Problems
  • Medications & Continence (for health professionals)

For information pamphlets on bladder and bowel control problems - contact the
New Zealand Continence Association


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